Implementation Timeline
Progressive 12-week journey to remission with clear milestones
1
WEEKS 0-2
Phase 1: Foundation
Anti-inflammatory
2
WEEKS 2-4
Phase 2: Energy Support
Add butyrate
3
WEEKS 4-6
Phase 3: Barrier Repair
Add curcumin
4
WEEKS 6-8
Phase 4: Microbiome
Add probiotic
1
Initial NF-κB Dampening & IL-22 Priming
WEEKS 0-2
Start These Compounds
A
Andrographis
60mg/day andrographolide
Key Actions
- Begin symptom diary tracking
- Establish baseline labs (CBC, CMP, calprotectin)
- Set medication alarms for consistency
- DIM primes IL-22 pathways
2
Energy & Barrier Support
WEEKS 2-4
Expected Changes
- Reduced urgency and frequency
- Less abdominal discomfort
- Improved stool consistency
- Better energy levels
3
Enhanced Barrier Repair
WEEKS 4-6
Add This Compound
C
Curcumin BCM-95
1600mg/day
Key Benefits
- Enhanced NF-κB blockade
- Barrier protein synthesis
- Mucosal healing acceleration
- Synergy with existing compounds
4
Microbiome Restoration
WEEKS 6-8
Add This Compound
B
B. longum Probiotic
450 billion CFU/day
Expected Outcomes
- IL-10 production boost
- Treg cell activation
- Immune tolerance restoration
- Stable remission approach
Milestone
~50% reduction in calprotectin
Mild digestive changes during week 1 are normal as your microbiome adapts.
TIPS FOR SUCCESS
Set Alarms
Phone reminders for each dose
With Meals
Better absorption (except EGCG)
Pill Organizer
Pre-sort weekly doses
Track Progress
Daily symptom diary